- PII
- S3034512X25110056-1
- DOI
- 10.7868/S3034512X25110056
- Publication type
- Article
- Status
- Published
- Authors
- Volume/ Edition
- Volume 80 / Issue number 11
- Pages
- 1175-1188
- Abstract
- A series of sorbents based on silica gel with zwitterionic functional layers attached via a spacer based on 1,4-butanediol diglycidyl ether was synthesized. The influence of structural fragments of the stationary phase on chromatographic properties in hydrophilic interaction chromatography was studied, and the multifunctional separation capabilities for neutral polar, hydrophobic, and negatively charged compounds were demonstrated. Based on the identified patterns, a sorbent with high separation capacity for carboxylic acids was developed, enabling the separation of 13 organic acids in 25 minutes with a resolution of at least 1.0.
- Keywords
- гидрофильная хроматография многофункциональные неподвижные фазы цвиттер-ионы гиперразветвленные сорбенты
- Date of publication
- 01.11.2025
- Year of publication
- 2025
- Number of purchasers
- 0
- Views
- 33
References
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